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Cancer, and Anti-Cancer Therapies and Treatments

This page contains a collection of news articles in pdf format on advances in cancer treatment and the anti-cancer properties of specific fruit, vegatables and other foodstuffs. Many individual foodstuffs have differential anti-cancer properties and some are cancer causing. Choosing a good combination of dietary factors can make a significant collective difference to human survival rates and cancer avoidance.

Cancer is in some ways a disease of the embryogenic pathway ( 1, 2, 3), so involves faulty cancer stem cells (1, 2, 3, 4) which may play a role in the spread of more malignant forms and also incite tissue transfer through secreted growth factors.

Cancer Immunology: It also invloves a breakdown of the immune system in which malignant cells are not recognized soon enough, resulting in the cancer adapting and producing adaptive mutations which shield immune signatures. Both of these mechanisms are targets of novel treatment.

The links are in no way comprehensive, but simply form a record of articles noticed and listed for future reference and a starting point for further research. Many of the foodstuffs are located under specific cancer types but could be active across a spectrum of cancers.

There is a more comprehensive discussion on foostuffs in the Chemical Complexity of Food.

A: Novel Cancer Treatments and Anti-cancer Agents

  1. Small-molecule drug drives cancer cells to suicide 2013
  2. Souped-up immune cells force leukaemia into remission 2012
  3. 'Drug holidays' beat cancer drug resistance in mice 2013
  4. Cancer's recruitment drive of healthy cells targeted 2012
  5. New 'Personalized' Drugs Dabrafenib and Trametinib Show Promise Against Melanoma, Lung Cancer 2012
  6. Drug-smuggling nanoparticles target tumours 2012 Nanocell's double hit on cancer 2005
  7. Pregnant women with cancer can safely have chemo 2012
  8. New cancer drug sabotages tumour's escape route 2012
  9. Cancer cells poisoned with sugar 2011
  10. Light 'promising' in cancer fight 2011
  11. Clostridium soil bacteria target solid tumors 2011
  12. Beta-blockers 'cut cancer spread' 2010
  13. Blocking a gene stops cancer cells spreading 2011
  14. 'Cancer hope' from diabetes drug Metformin 2009
  15. DCA: Cheap, 'safe' drug DCA kills most cancers 2011 DCA Experimental cancer drug resurfaces 2010
    Many cancers depend on glycolysis, probably partly because they begin with a poor blood supply. DCA inhibits the embryonic glycolysis pathway, which is not used in adults so has relatively few side effects, and encourages mitochondrial apoptosis.
  16. Mitochondria: The Organelle of Death 2010 A summary about the properties of mitochondria as agents of programmed cellular death, or apostosis, resisting cancer.
  17. Troubleshooters that block cancer 2009
  18. New cancer drug Olaparib 'shows promise' 2009
  19. Virus accomplice helps drugs fight cancer 2009
  20. Drug salinomycin shows cancer stem cells not invulnerable 2009
  21. Universal cancer marker shows new treatment options 2010
  22. Cancer vaccine implant 'can attack and kill tumours' 2009
  23. Asprin: Aspirin a 'no brainer' against cancer after screening 2012Small daily aspirin dose 'cuts cancer risk' 2010 Aspirin 'helps protect against bowel cancer' 2010 Aspirin Cuts Breast Cancer Survivors' Risk 2010 Aspirin 'cuts bowel cancer risk' 2005 Aspirin cuts stomach cancer risk 2009 Daily aspirin 'blocks bowel cancer' 2011 Daily aspirin 'prevents and possibly treats cancer' 2012 Aspirin 'may prevent skin cancer' 2012

B: Mechanisms of Cancer and Cancer Immunity

  1. Enzyme behind cancer spread found 2009
  2. Protein predicts which cancers will spread 2011
  3. Scientists crack 'entire genetic code' of cancer 2009
  4. Cancer 'danger receptor' found 2009
  5. Cell Therapy fights Leukemia 2011
  6. Tumours ramp up recycling efforts 2011

C: Cancer and Cancer-fighting Viruses

  1. Trojan-horse therapy 'completely eliminates' cancer in mice Dec 12
  2. Liver cancer survival time tripled by virus 2013
  3. Virus therapy sparks hope for cancer patients 2011
    Scientists say they have found a genetically engineered virus that can kill tumor cells without harming the patient.
  4. 'One in six cancers worldwide are caused by infection' 2012
  5. 'Anti-cancer virus' shows promise 2011
  6. Herpes virus used to treat cancer 2010
  7. Many under-16s carry cancer virus 2007
  8. Virus helps show prostate cancer spread 2008

D: Angiogenesis inhibitors and Monoclonal antibodies. Cancers need to catalyse a blood suplly to grow so preventing this is one route to preventing cancer. Epicatechin-gallate in tea and cannabis compounds are natural angiogenesis inhibitors. There are also very high tech monoclonal antibody inhibitors.

  1. Monoclonal antibody therapy
  2. Angiogenesis Inhibitors Therapy
  3. Understanding Angiogenesis
  4. Bevacizumab Monoclonal Angiogenesis Inhibitor
  5. Herceptin a monoclonal antibody
  6. Anti-Angiogenic Cancer Drugs Include Cannabis, Ginger, Curcumin, Omega-3
  7. Cancer drug Cilengitide 'fuels tumour growth' 2009
  8. Targeted treatment tested as potential cancer cure 2011
  9. Personalized cancer therapy gets closer 2009

E: Cancer and Medicinal Species and Food

  1. Chemical Complexity of Food Article outlining the nutrient, medicinal and anti-cancer properties of plants and other food species.
  2. US scientists challenge scares about food links to cancer 2012
  3. Pressure mounts for retraction of GM crop-cancer study 2012
  4. Herbal tea could help beat breast cancer 2012 Fagonia
  5. Death carrot' could hold the key to new cancer drugs 2012
  6. Red meat increases death, cancer and heart risk, says study 2012
  7. Oregano, a cancer fighting 'super spice' 2012
  8. Scientists discover how wild mushroom cancer drug works 2009
  9. THC (marijuana) helps cure cancer says Harvard study 2007 Cannabis compound 'halts cancer' 2007
  10. Cannabis and immunity - a reference file Marijuana testicular cancer link 2009
  11. Anti-Cancer boost from whole carrots 2009
  12. Brazil nut a day keeps low selenium, cancer at bay: Otago research 2008 Selenium and Prostate Cancer
  13. Sulforaphane and Sinigrin - Broccoli chemical's cancer check 2006 Brassicas from mustard, through brussel sprouts to broccoli and cabbage contain anti-cancer substances.
  14. Broccoli compound can kill cancer Dec 12
  15. Olive oil 'can cut cancer risk' 2006 Olive oil acid 'cuts cancer risk' 2005
  16. How spicy foods can kill cancers 2007
  17. Lycopene anti-cancer 'Cancer-fighting tomato' on sale 2006
  18. Curry spice 'kills cancer cells' 2009 Curry spice may help cancer fight 2005 Curry's ability to fight cancer put to the test 2012
  19. Vitamin D 'can lower cancer risk' 2005 Lung cancer 'link to lack of sun' 2007
  20. Mint leaf starves cancer to death 2004
  21. Green vegetables may cut cancer risk 2009 Mediterranean diet 'cuts lung disease risk' 2007
  22. Vegetarians 'avoid more cancers' 2009 Five-a-day frut and veg 'will not cut cancer' 2010
  23. Marinating 'may cut cancer risk' 2008 Well-done meat doubles bladder cancer risk 2010
  24. Morphine 'might spread cancer' 2009 Animal fats pancreas cancer link 2009
  25. Health effects and anti-cancer properties of green tea
  26. Milk wrecks the health benefits of tea 2007
  27. Antioxidants in Green Tea increased effectiveness with Lemon/Orange Juice high in Vitamin C 2007
  28. Green tea supplements stop cancer drug bortezomib working 2009 Bortezomib
  29. Fibre and whole grains 'reduce bowel cancer risk' 2011

F: Cancer Prognosis and Lifestyle

  1. Men's cancer risk 'to climb to one in two' 2012
  2. Fertility problems linked to cancer in offspring 2012
  3. Thank grandmothers for lower incidence of cancer 2012
  4. Over 40% of cancers due to lifestyle, says review Dec 11
  5. Warning over global cancer levels 2011
  6. Loneliness makes cancer 'more likely and deadly' 2009
  7. Marriage 'cancer survival impact' 2009
  8. Depression 'cuts cancer survival' 2009
  9. Exercise 'cuts colon cancer risk' 2009 Fitness 'cuts colon cancer risk' 2006
  10. Healthy lifestyle turns off genes that cause cancer 2008
  11. Sedentary life 'speeds up ageing' 2008
  12. Running 'can slow ageing process', prevent cancer 2009
  13. Prolonged Sitting Linked to Breast and Colon Cancers 2011

G: Lung cancer

  1. Two questions on Lung Cancer Treatment
  2. Lung cancer drug erlotinib or Tarceva 'extends life' 2010
  3. Anti-estrogen Drug (Tamoxifen) reduces lung cancer deaths 2011 Tamoxifen
  4. Broccoli helps clear damaged lungs 2011
  5. Insulin-Like Growth Factor and Lung Cancer 2006 See Resveratrol, which appears to stimulate sirtuins which both prolong life and inhibit the IGF pathway.
  6. Drugs boost lung cancer survival 2005
  7. Deadliest small-cell lung cancer breakthrough 2009
  8. Beans and soya beat lung cancer 2005 'Eat more beans' to stop cancer
  9. Cabbages 'cut lung cancer risks' 2005
  10. Cannabis compound slows lung cancer in mice 2007 Marijuana Compound THC May Fight Lung Cancer 2007
  11. Cannabis use and risk of lung cancer 2007 Cannabis and tobacco smoke are not equally carcinogenic 2005
  12. Green tea 'may block lung cancer' 2010
  13. Targeted treatment tested as potential cancer cure 2011

H: Breast, Uterine and Ovarian cancer

  1. Benefits of mammograms under fire 2012
  2. Squeeze the cancer out of breasts - research 2012
  3. Way to spot breast cancer years in advance 2012
  4. Routine Mammograms Lead to Overdiagnosis of Breast Cancer 2012
  5. Breast screening advice updated amid controversy over harms 2012
  6. Breast cancer rules rewritten in 'landmark' study 2012
  7. Taller women face greater cancer risk - study 2012
  8. Tamoxifen
  9. Taxol
  10. Herceptin
  11. Herbal tea could help beat breast cancer 2012 Fagonia
  12. 'Fatty apron' fuels ovary cancer 2011
  13. Thiostrepton holds key to blocking breast cancer 2011
  14. Drug hope for aggressive breast cancer 2011
  15. Scientists find why tamoxifen fails some breast cancers 2010
  16. 'Statins' for cancer could prevent many breast cancers 2011
  17. Cholesterol drug cancer warning 2008
  18. Third of breast cancer 'harmless' 2009
  19. Coffee mooted as a breast cancer preventer 2011
  20. Key breast cancer 'driver' gene found 2011
  21. Breast cancer screening does 'more good than harm' 2010
  22. Breast cancer screeing under review 2011
  23. Cannabis Compound Stops Spread of Breast Cancer 2007
  24. Pill 'lowers ovarian cancer risk' but increases breast cancer risk 2011
  25. Breast cancer link to small amount of alcohol 2011
  26. Grapefruit link to breast cancer 2007

I: Bowel cancer

  1. 'Promising results' for bowel cancer breath-test 2012
  2. Two bowel cancer genes discovered 2012
  3. Gene offers bowel cancer 'shield' 2009
  4. 'Cancer hope' from WWII-era drug methotrexate 2009
  5. Bowel cancer sigmoidoscopy test could save many lives 2010
  6. Ginger 'could halt bowel cancer' 2003
  7. Both broccoli which reduces mutations and brussel sprouts which encourage cell apoptosis sef-destructing pre-cancerous polyps are active against bowel cancer.

J: Melanoma and Skin Cancer

  1. Skin cancer drug hopes raised by study 2013
  2. Skin cancer treatment: vemurafenib Biggest breakthrough in 30 years 2011
  3. Melanoma drug ipilimumab wins US approval 2011 ipilimumab (Yervoy) trials website
  4. Drug R7204 hope for advanced melanoma 2009 Hope over new skin cancer therapy 2009
  5. Pill RG7204 slows spread of skin cancer in half of cases 2011
  6. Antibody Therapy Lengthens Survival of Metastatic Melanoma Patients in Large Clinical Trial 2010
  7. Combination Antibody Therapy Shows Promise in Metastatic Melanoma 2011

K: Pancreatic cancer

  1. Processed meat 'linked to pancreatic cancer' 2012
  2. Pancreas cancer drug failure clue 2009
  3. New lead on deadly pancreatic cancer 2011
  4. Pancreatic cancer therapy 'hope' 2009

L: Brain cancer

  1. Dental x-rays linked to brain tumours 2012
  2. Cannabis extract shrinks brain tumours 2004
  3. Genomics boosts brain-cancer work 2010

M: Prostate Cancer

  1. Prostate cancer blood test causes controversy 2012
  2. New prostate cancer treatment may reduce side-effects 2012
  3. Is oral contraceptive pill fuelling prostate cancer? 2011
  4. Alpha radiation treats prostate cancers 2011
  5. Urine predicts prostate cancer risk 2011
  6. Mustard and Broccoli Beat Prostate Cancer
  7. Index finger length prostate cancer clue 2010
  8. High risk prostate cancer death 'cut with radiation' 2010
  9. Broccoli 'stops' prostate cancer 2007
  10. Cannabis compounds fight prostate cancer 2009
  11. Resveratrol, Powerful Protection Against Prostate Cancer - Daily Red Wine Cuts Prostate Cancer Risk By Half
  12. Grape Compound Prolongs Life, Fish Study Concludes 2006
  13. Drug Abiraterone for deadly prostate cancer 2008
  14. Gene mutation slashes prostate cancer survival time 2007
  15. US researchers claim beer and coffee can slash prostate cancer risk 2009
  16. Vitamin D and Painkiller Naproxen Slow Prostate Cancer 2005 Vitamin D treatment in prostate cancer 2009
  17. Coffee could help cut prostate cancer risk, says study 2009
  18. Coffee 'cuts prostate cancer risk' US study suggests 2011
  19. Prostate drug dutasteride 'may cut cancer risk' 2010
  20. Male tea drinkers 'at greater risk of prostate cancer' 2012 Green tea 'slows prostate cancer' 2009 Drinking Green Tea Daily lowers Prostate Cancer Risk
  21. Green Tea Kills Prostate Cancer Cells 1998
  22. Meat 'ups prostate cancer risk' 2008
  23. Pomegranate Juice 'can slow prostate cancer' 2006 Pomegranates 'slow tumour growth' 2005
  24. Prostate cancer vaccine Provenge wins US approval 2010
  25. Multi-dimensional Prostate Anti-Cancer Diet Supplement
  26. The ongoing debate in NZ on PSA screening 2011
  27. Prostate screening has no benefit 2011 Professor urges limits on prostate-cancer testing 2011
  28. Doubt over prostate cancer test 2006 Prostate screening under scrutiny 2009
  29. Prostate cancer gene screening 'hope' 2008 Killer prostate cancer test Hsp-27 hope 2009
  30. Prostate cancer urine test hope 2009
  31. Statins link to healthy prostate 2009
  32. Virus XMRV linked to prostate tumours 2009
  33. Brisk walks fight prostate cancer 2011
  34. Resveratrol: Red wine may reduce risk of prostate cancer: study 2007
  35. PTEN p53 Clue to stopping prostate cancer 2005
  36. Red clover helps treat prostate cancer 2002

N: Alcohol and cancer

  1. Drinking over recommended limit 'raises cancer risk' 2011
  2. Drink a day increases cancer risk 2009